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So you have Dysbiosis. What's next?

Why would you choose to follow a natural anti-microbial strategy rather than the standard conventional medicine treatment? 

Dysbiosis is a general term that describes an unhealthy gut microbiome – defined by the imbalance between beneficial bacteria (and other microbes) and harmful bacteria. A dominance of pathogenic bacteria and other harmful microorganisms can lead to a wide variety of frustrating symptoms and health conditions. 

But no worries. If you and your practitioner think you have dysbiosis, you’re in the right place!

Drawing on both scientific research and the healing traditions of various cultures, we recommend a botanical (plant-based) strategy to remove harmful microbes and tame the inflammatory effects caused by the microbes themselves. We’ve seen thousands of clients regain proper gut function with the help of these formulas. Unlike many conventional pharmaceuticals, herbal formulas often come with built-in positive side effects.

For example, a plant-derived ingredient can help the body remove harmful microbes while at the same time easing intestinal and systemic symptoms like cramping, inflammation, and oxidative stress. Harmful microbes and microbial overgrowth can cause inflammation and oxidation, so nature’s way of combining antimicrobial, anti-inflammatory, and antioxidant actions in the same botanical ingredient is mind-blowing. 

Here’s the basic strategy . . . .

 

1. antimicrobial formulas to help your gut combat harmful microorganisms

Paracleanse contains herbs that have been show to help combat a wide variety of microbes – while benefitting the digestive tract and boosting general wellness at the same time.

Nopal: Otherwise known as the prickly pear, this common cactus with bright red fruits spread around the world like wildfire in the last several centuries. It’s native to the southern US and Mexico and has long been used by indigenous people to lower fevers, treat infections, and even calm angry moods. This medicinal plant has antimicrobial properties and can calm spasms of the digestive tract.¹ Beyond these actions, it’s a potent antioxidant and anti-inflammatory.² 

Noni Fruit: A trendy health food nowadays, noni has been used for generations among Hawaiians and Tahitians to treat a wide variety of conditions, including infections and intestinal parasites. Laboratory tests have demonstrated its antifungal and antibacterial actions. It enhances immune cells, reduces inflammation, and calms intestinal spasms.³ 

Turmeric: The main active ingredient in turmeric, curcumin, is well-known for its confirmed ability to reduce inflammation and oxidation. Traditionally in Asia, however, turmeric juice was widely used to treat intestinal worms. Research shows it is effective against a wide variety of parasites, including worms, giardia lamblia, and protozoa, including plasmodium, which causes malaria. Importantly, some types of drug-resistant malaria respond to turmeric in mice models.4

Green Tea Leaf Extract: The Classic of Tea, an early treatise describing the etiquette and healing effects of drinking tea, was written in 800 AD. Modern scientists have discovered that the catechins in green tea have a wide variety of medicinal properties. Laboratory and animal experiments show that catechins can kill protozoa, worms, and mites. Like many botanical extracts, they can work even on drug-resistant strains.5

The second product in our antimicrobial gut wellness program is B-cleanse, which contains plant-derived ingredients that support immunity, the intestinal lining, and detoxification as well as killing bacteria and other pathogens. 

Olive leaf extract: Olive leaves have been used to treat illness since ancient times. Modern laboratory experiments have shown that OLE can almost completely eradicate the three bacteria that most frequently cause food poisoning (Listeria, E.coli, and Salmonella).6  In addition, the active ingredients in OLE kill fungi like Candida albicans, a common cause of intestinal yeast infections. Since OLE works against drug-resistant microbes, it has received a great deal of attention in recent years.7

Coriander: Also known as cilantro, this herb does more than add great flavor to food. Dating back to ancient Israel, Egypt, and Greece, it was used as a medicine by Hippocrates himself. Through the ages, it was used to calm nerves, relieve digestive cramps and gas, and soothe an upset stomach.8 Now research shows its ability to inhibit the growth of bacteria and to kill a variety of bacteria, worms, yeasts, and fungi by damaging the pathogens’ cell membranes.9

Reishi mushroom: Another ancient remedy, this time from ancient China, is the Reishi mushroom, which grows on living and dead trees. Called “the mushroom of immortality,” its 400 bioactive compounds that scientists have now examined—with dozens of beneficial uses for health—can almost justify its reputation. It has antioxidant, anti-cancer, and neuro-protective effects. Research shows it inhibits a wide range of bacteria and viruses.10

Coriolus mushroom: Animal studies have confirmed the ability of another mushroom, coriolus, to inhibit various bacteria, including Listeria, strep, and E. coli, as well as Candida albicans. Laboratory analyses show that the mushroom extract damages the cell walls of the pathogens.11

Spectrum BR, the third antimicrobial formula we’ve chosen, is designed to help the body resist pathogenic yeast overgrowth. It includes: 

Berberine: A natural chemical found in a variety of plants including goldenseal, barberry, Oregon grape, coptis, and philodendron. It is a powerful antimicrobial, especially against yeasts. Lab experiments reveal that it can destroy the cell wall, mitochondria, and biofilm of even multi-drug resistant strains of Candida. 12

Ginger: The same ginger root you use in cooking has been used for centuries around the world as a medicinal plant. As renowned herbalist Stephen Buhner states, “Everyone not trapped in a technological culture uses ginger for healing.”13 

Beloved as a digestive aid, painkiller, and remedy for colds and flus, it has well-documented anti-inflammatory and antioxidant properties, too. Lately its antifungal actions have drawn attention. As yeast infections become more common, more and more strains are becoming resistant to standard antifungal drugs. Ginger is a possible solution. In one study, for example, it was found to kill certain strains of Candida more effectively than some commonly used drugs.14

Licorice: After four millennia of use as a medicinal herb, licorice is still valued for its healing qualities. Scientists have now isolated 320 compounds in this herb, several of which have the ability to inhibit or kill microbes, including bacteria, fungi, and viruses. 

Specifically, some of the chemicals in licorice prevent Candida from switching from its yeast to fungal form, a process that makes yeast infections particularly difficult to eradicate.15

2. Targeted anti-inflammatories to help your body repair from harmful microbes

inflam-eze supplement

While working to resolve dysbiosis, your gut needs consistent support for the inflammation in the lining of the intestines caused by the pathogenic microbial overgrowth. Why?

  • Inflammation creates holes in the intestinal lining that leak macroparticles into the bloodstream. 
  • The macroparticles are perceived as invaders by the immune system.
  • This immune system response tends to create an inflammatory cascade throughout the body.
  • Unchecked inflammatory cascades lead to a long list of symptoms and serious health conditions.

If you want to resolve your dysbiosis, you need to support your system with research-based botanical formulas to reduce gut inflammation. Inflam-Eze is our favorite botanical formula designed to help repair the lining of the small and large intestine. Without an anti-inflammatory, you are unlikely to make progress in the program.

Dynamic Inflam-Eze is a high-powered nutritional supplement that provides a balance of carbohydrates, protein, and fats combined with a plethora of anti-inflammatory and antioxidant botanical ingredients. Turmeric, ginger, Indian frankincense, and green tea extract are just some of the healing nutrients that help calm the digestive tract during detoxification programs—or any time.

3. Restore your beneficial bacteria and strengthen your gut’s immune system

Finally, after the antimicrobial strategy, you should spend at least 90 days supporting new growth of optimal communities of beneficial and protective gut bacteria (with Probiotic Pro) and revitalize the gut immune tissue (with Immune PRP Pro). 

After all, you don’t want to end up right back where you started!

Probiotic Pro: The good bacteria in your GI tract help it metabolize food, absorb nutrients, and keep foreign microbes in check. They play an important role in immunity, and they even help your mood and cognitive functions via the gut-brain axis.16 

This multi-strain probiotic formula contains Bifidobacterium lactis, which appear to be the most important organisms in the intestine for promoting a healthy intestinal lining. It also contains multiple strains of Lactobacillus, which have been shown to alleviate the symptoms of Irritable Bowel Syndrome.17

Immune PRP Pro: To supercharge your gut recovery and repair program, add this final piece of the puzzle that helps improve immunity and strengthen the intestinal tract using bovine colostrum. Since calves don’t receive antibodies in utero, the first days of milk they receive after birth are ultra-rich in immune-enhancing compounds. 

Bovine colostrum has been shown to have potent benefits for humans. It fights unwanted microbes, inhibits the ability of pathogens to adhere to the intestinal wall, and helps normalize the balance of good bacteria in the gut. It not only attacks pathogens directly, but it stimulates the body’s immune system to more effectively fight off infections. Colostrum contains 20 different growth factors that can speed the healing of the intestinal lining. 

Finally, a component of bovine colostrum, PRP (proline-rich polypeptide) calms inflammatory processes in the gut and throughout the body.18 With all these benefits, Immune PRP Pro is the perfect capstone for a gut wellness program. 

Miranda Brist - phytotherapist and health and wellness coach at the Global Wellness Lab

Dysbiosis is complicated. But I’ve walked hundreds of folks through this program – and I’ve seen a myriad of physical symptoms resolve. Ultimately, it’s you + the COMBINATION of the correct supplements, in the right amounts, at the right times that gets results. You will also need the tools to troubleshoot common symptoms that arise during the cleanse. All these things and more are at your fingertips in our program handbook. 

If you and your practitioner are  ready start your journey towards better stomach health, just download our Gut Wellness Program Handbook. Any questions? I’m here for you. 

Your Lab partner,
Miranda Brist

Download the Gut Wellness Program handbook to start your gut restoration journey.

inflam-eze supplement

Sources

1. Baldassano S., et al. Inhibitory effects of indicaxanthin on mouse ileal contractility. European Journal of Pharmacology. May 2011; 658(2–3,11):200-205.

2. Patel S. Opuntia cladodes (nopal): Emerging functional food and dietary supplement. Mediterranean Journal of Nutrition and Metabolism. 2014;7:11–19. DOI:10.3233/MNM-140003

3. Ali M, Kenganora M, Manjula, SN. Health Benefits of Morinda citrifolia (Noni): A Review. Pharmacognosy Journal. 2016;8(4).

4. Shahiduzzaman MD, Daugschies A. Curcumin: A natural herb extract with antiparasitic properties. In Nature Helps, June 2011, pp. 141-152. DOI:10.1007/978-3-642-19382-8_6

5. Argüello-García R, Quiñonez-Bastidas GN. Catechins as emerging and promising antiparasitic agents. Biomedical Journal of Scientific & Technical Research. September 2020;30(1):23084-23088. DOI: 10.26717/BJSTR.2020.30.004895

6. Liu Y, McKeever LC, Malik NS. Assessment of the antimicrobial activity of olive leaf extract against foodborne bacterial pathogens. Front Microbiol. 2017;8:113. doi:10.3389/fmicb.2017.00113

7. Borjan D, Leitgeb M, Knez Ž, Hrnčič MK. Microbiological and antioxidant activity of phenolic compounds in olive leaf extract. Molecules. 2020;25(24):5946. doi:10.3390/molecules25245946

8. Abascal K, Yarnell E. Cilantro—Culinary herb or miracle medicinal plant? Alternative and Complementary Therapies. 2012;18(5):259-264.

9. Silva F, Domingues FC. Antimicrobial activity of coriander oil and its effectiveness as food preservative. Critical Reviews in Food Science and Nutrition. 2017;57(1):35-47.

10. Cör D, Knez Ž, Hrnčič K, Antitumour M. Antimicrobial, antioxidant and antiacetylcholinesterase effect of Ganoderma lucidum terpenoids and polysaccharides: A review. Molecules. 2018;23(3):649. doi:10.3390/molecules23030649

11. Matijašević D, Pantić M, Rašković B, et al. The antibacterial activity of Coriolus versicolor methanol extract and its effect on ultrastructural changes of Staphylococcus aureus and Salmonella enteritidis. Front Microbiol. 2016;7:1226. doi:10.3389/fmicb.2016.01226

12. da Silva AR, de Andrade Neto JB, da Silva CR, et al. Berberine antifungal activity in Fluconazole-resistant pathogenic yeasts: Action mechanism evaluated by flow cytometry and biofilm growth inhibition in Candida spp. Antimicrob Agents Chemother. 2016;60(6):3551-3557. doi:10.1128/AAC.01846-15

13. Buhner, S. Herbal Antivirals: Natural Remedies for Emerging Resistant & Epidemic Viral Infections. North Adams, MA: Storey Publishing, 2013.

14. Aghazadeh M, Zahedi Bialvaei A, Aghazadeh M, et al. Survey of the antibiofilm and antimicrobial effects of Zingiber officinale (in vitro study). Jundishapur J Microbiol. 2016;9(2):e30167. doi:10.5812/jjm.30167

15. Wang L, Yang R, Yuan B, Liu Y, Liu C. The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb. Acta Pharm Sin B. 2015;5(4):310-315. doi:10.1016/j.apsb.2015.05.005

16. Wu HJ, Wu E. The role of gut microbiota in immune homeostasis and autoimmunity. Gut Microbes. 2012;3(1):4-14. doi:10.4161/gmic.19320

17. Quigley EM. Gut bacteria in health and disease. Gastroenterol Hepatol (N Y). 2013;9(9):560-569.

18. Playford RJ, Weiser MJ. Bovine colostrum: Its constituents and uses. Nutrients. 2021;13(1):265. doi:10.3390/nu13010265